PODCAST: Promise Shown in Different Approach to Alzheimer’s

AgeneBio is developing drugs to treat the pre-dementia stage of Alzheimer’s disease, and other neurological and psychiatric conditions. The company announced encouraging mid-stage results for its lead therapeutic, which works by quieting hyperactivity in the hippocampus portion of the brain, which plays a critical role in the formation of memory. We spoke to Jerry McLaughlin,…

An Epilepsy Drug to Prevent Cognitive Decline?

An atypical antiepilepsy drug is being investigated for a possible role in treating patients with mild cognitive impairment (MCI). A new study shows that low doses of levetiracetam reduced the overactivation in subregions of the hippocampus that have been linked to amnestic MCI (aMCI) — the dentate gyrus (DG) and the cornu ammonis 3 (CA3)…