Posts for category: In the News

PODCAST: Promise Shown in Different Approach to Alzheimer’s

AgeneBio is developing drugs to treat the pre-dementia stage of Alzheimer’s disease, and other neurological and psychiatric conditions. The company announced encouraging mid-stage results for its lead therapeutic, which works by quieting hyperactivity in the hippocampus portion of the brain, which plays a critical role in the formation of memory. We spoke to Jerry McLaughlin,…

An Epilepsy Drug to Prevent Cognitive Decline?

An atypical antiepilepsy drug is being investigated for a possible role in treating patients with mild cognitive impairment (MCI). A new study shows that low doses of levetiracetam reduced the overactivation in subregions of the hippocampus that have been linked to amnestic MCI (aMCI) — the dentate gyrus (DG) and the cornu ammonis 3 (CA3)…

Clinical Trial Reveals Promising Brain Therapeutic Drug for the Pre-Dementia Stage of Alzheimer’s Disease

Pharmaceutical company AgeneBio recently announced the publication of results of a Phase 2 clinical trial based on the company’s therapeutic product AGB101 for the pre-dementia stage of Alzheimer’s disease in the journal NeuroImage: Clinical. The study entitled “Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task…

Could epilepsy drug help treat Alzheimer’s disease?

A drug commonly used to treat epilepsy could help “slow down” the progress of Alzheimer’s disease, reports The Daily Express. According to the news story, the drug levetiracetam was shown to “help restore brain function and memory”. The story is based on a study analysing the short-term effect of the drug in 54 people with…

Agenebio’s AGB101 enroute to phase III on back of aMCI phase II

Trying to translate discovery research and early clinical data into phase III success has proved the bane for drug developers working in Alzheimer’s disease. But executives at Agenebio Inc., which is gearing up to start a phase III study in the second half of this year with lead product AGB101, think their approach will be…

New Drug Approach May Delay Alzheimer’s Dementia

A new drug approach helped restore the memory of elderly patients who are at high risk for dementia due to Alzheimer’s, and may potentially delay the onset of this debilitating disease, according to new research.